SCHEMBL9101839

SCHEMBL9101839

CCCS(=O)(=O)ON1c2ccccc2Oc2cccc(-c3nccc(C)n3)c21

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
P2RX4 Q99571 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101809 0.89 USP2 (0.31)
SCHEMBL9105645 0.89
SCHEMBL9100310 0.89
SCHEMBL9101679 0.89
SCHEMBL9105272 0.87
SCHEMBL9102285 0.85 TGFBR1 (0.35) TGFBR1P2RX4
SCHEMBL9100065 0.83 BCHE (0.33) TGFBR1RXFP1
SCHEMBL9102910 0.83 P2RX4 (0.31) P2RX4
SCHEMBL9103550 0.81 MEN1 (0.31) RXFP1P2RX4
SCHEMBL9104689 0.79 SGMS2 (0.32) RXFP1P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed