SCHEMBL9102293

SCHEMBL9102293

CCCCc1cccnc1-c1cccc2c1N(OS(=O)(=O)CCC)c1ccccc1S2

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.33
THRB P10828 2/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
GFER P55789 1/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 2/20 0.31
APLNR P35414 2/20 0.30
HTT P42858 1/20 0.30
BCL2L2 Q92843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102738 0.94 HDAC3 (0.34) BCHETHRBHDAC3HDAC1HDAC6
SCHEMBL9104104 0.93 THRB (0.36) BCHETHRBHDAC3HDAC1HDAC6
SCHEMBL9104005 0.87 BCHE (0.35) BCHEHDAC3HDAC1HDAC6MAPT
SCHEMBL9100421 0.86 BCHE (0.32) BCHEGFER
SCHEMBL9101795 0.86 BCHE (0.35) BCHETHRBHDAC3HDAC1HDAC6
SCHEMBL9101410 0.86 LMNA (0.32) BCHETHRBHDAC3HDAC1HDAC6
SCHEMBL9105875 0.85 BCHE (0.39) BCHENR1H2NR1H3GFERMAPT
SCHEMBL9101867 0.84 NR1H2 (0.32) NR1H2NR1H3APLNRBCL2L2
SCHEMBL9104286 0.81 BCHE (0.34) BCHEGFERMAPT
SCHEMBL9100398 0.81 NOX1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed