SCHEMBL9104005

SCHEMBL9104005

CCCS(=O)(=O)ON1c2ccccc2Sc2cccc(-c3ncccc3C)c21

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BCHE P06276 3/20 0.35
MAPT P10636 3/20 0.34
LMNA P02545 1/20 0.32
TP53 P04637 2/20 0.32
HTT P42858 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9104104 0.90 THRB (0.36) BCHEMAPTLMNATP53HTT
SCHEMBL9101410 0.89 LMNA (0.32) BCHEMAPTLMNATP53HTT
SCHEMBL9101795 0.89 BCHE (0.35) BCHEMAPTLMNAHTTHDAC3
SCHEMBL9102738 0.89 HDAC3 (0.34) BCHEMAPTLMNAHTTHDAC3
SCHEMBL9102293 0.87 BCHE (0.33) BCHEMAPTLMNAHTTHDAC3
SCHEMBL9104590 0.86 BCHE (0.33) BCHEFNTAFNTB
SCHEMBL9105527 0.84 BCHE (0.41) BCHEMAPTHTT
SCHEMBL9103550 0.83 MEN1 (0.31) MAPTKMT2A
SCHEMBL9100065 0.82 BCHE (0.33) BCHEMAPTHTT
SCHEMBL9103537 0.80 BCHE (0.31) BCHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed