Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | RAD52 | P43351 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104807 | 0.93 | MAPT (0.73) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL22024566 | 0.89 | MAPT (0.72) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL48681 | 0.88 | MEN1 (0.58) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL30115197 | 0.88 | MEN1 (0.58) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL30115198 | 0.88 | MEN1 (0.58) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL48847 | 0.87 | MEN1 (0.57) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL8444747 | 0.87 | MEN1 (0.57) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL9102418 | 0.85 | MAPT (0.53) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL9100289 | 0.85 | MAPT (0.50) | MAPTMAPK1TDP1TP53CYP3A4 | |
| SCHEMBL49291 | 0.84 | PIM1 (0.59) | MAPTMAPK1TDP1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |