Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.58 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.48 |
| ▸ | KDM5C | P41229 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KDM6B | O15054 | 3/20 | 0.48 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL4372083 | 1.00 | LMNA (0.58) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28684497 | 0.97 | LMNA (0.55) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL11804466 | 0.92 | LMNA (0.50) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Adipic Acid SCHEMBL27649164 | 0.88 | LMNA (0.61) | LMNAOR51E2SLC22A6TSHRNFKB1 | |
| Adipic Acid SCHEMBL5138045 | 0.88 | LMNA (0.61) | LMNAOR51E2SLC22A6TSHRNFKB1 | |
| Succinic Acid SCHEMBL6753145 | 0.87 | LMNA (0.46) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28879220 | 0.87 | TDP1 (0.50) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL173955 | 0.87 | LMNA (0.65) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL11059037 | 0.87 | LMNA (0.65) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Methacrylic Acid SCHEMBL22191352 | 0.87 | TDP1 (0.50) | LMNASLC15A2EGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117539124-B | Red photoresist composition with good thermal stability | 江苏雅克科技股份有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-117645675-A | Methacrylic acid succinic acid di-esterified starch, preparation method thereof and application thereof in cornea defect in-situ filling agent | 华南理工大学 | 2024-03-05 | — | — | CN | claimed |
| CN-117539124-A | Red photoresist composition with good thermal stability | 江苏雅克科技股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| US-11366388-B2 | Color photoresist composition | TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2022-06-21 | — | — | US | claimed |
| CN-109689815-B | Heat-curable conductive adhesive | 三键有限公司 | 2022-06-14 | — | — | CN | claimed |
| US-20200409267-A1 | COLOR PHOTORESIST COMPOSITION | TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2020-12-31 | — | — | US | claimed |
| US-20200399475-A1 | COLOR PHOTORESIST COMPOSITION | TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2020-12-24 | — | — | US | claimed |
| WO-2020228169-A1 | COLOR PHOTORESIST COMPOSITION | 深圳市华星光电技术有限公司 | 2020-11-19 | — | — | WO | claimed |
| CN-110187602-B | Color photoresist composition | 深圳市华星光电技术有限公司 | 2020-10-13 | — | — | CN | claimed |
| CN-108535961-B | Color photoresist composition | 深圳市华星光电技术有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-111427234-A | Color photoresist composition | TCL华星光电技术有限公司 | 2020-07-17 | — | — | CN | claimed |
| CN-108508700-B | Dye monomer and color photoresist | 深圳市华星光电技术有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-108089402-B | Pigment dispersion system and preparation method thereof and colored photoresist | 深圳市华星光电技术有限公司 | 2019-10-11 | — | — | CN | claimed |
| CN-108535961-A | A kind of colour photoetching compositions | 深圳市华星光电技术有限公司 | 2018-09-14 | — | — | CN | claimed |
| CN-108089402-A | Pigment dispersion system and preparation method thereof and colored photoresist | 深圳市华星光电技术有限公司 | 2018-05-29 | — | — | CN | claimed |
| CN-107987207-A | Double cross connection acrylic entity plane materiel and preparation method thereof | 珠海市盛西源机电设备有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-101802709-B | Pigment dispersion composition, photoresist composition for color filter comprising the same, and color filter using the same | CHEIL WOOL TEXTILE CO LTD | 2013-03-27 | — | — | CN | claimed |
| US-7923480-B2 | Photocurable hygroscopic composition and organic EL device | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-04-12 | — | — | US | claimed |
| CN-101802709-A | Pigment dispersion composition, photoresist composition for color filter comprising the same, and color filter using the same | CHEIL WOOL TEXTILE CO LTD | 2010-08-11 | — | — | CN | claimed |
| US-5523340-A | ORGANIC PIGMENT, POLYMER CONTAINING PYRROLIDONE AND HYDROXY GROUPS, SECOND POLYMER WITH CARBOXYL AND HYDROXY GROUPS, AMINE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1996-06-04 | — | — | US | claimed |