Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21691991 | 0.83 | P2RX4 (0.37) | P2RX4ALDH1A1 | |
| SCHEMBL9104148 | 0.80 | P2RX4 (0.40) | LMNAMEN1KMT2AP2RX4ALDH1A1 | |
| SCHEMBL13023981 | 0.79 | LMNA (0.36) | LMNASMN1; SMN2FLT3GSK3BNPSR1 | |
| SCHEMBL9106473 | 0.77 | P2RX4 (0.37) | P2RX4 | |
| SCHEMBL9100589 | 0.77 | KMT2A (0.49) | SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL11420554 | 0.76 | KDM4E (0.43) | SMN1; SMN2P2RX4ALDH1A1 | |
| SCHEMBL13022593 | 0.74 | FLT3 (0.35) | LMNASMN1; SMN2FLT3GSK3BNPSR1 | |
| SCHEMBL20172203 | 0.72 | P2RX4 (0.37) | SMN1; SMN2MEN1KMT2AP2RX4 | |
| SCHEMBL30462881 | 0.72 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2P2RX4ALDH1A1CYP2C9 | |
| SCHEMBL5487603 | 0.72 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2P2RX4ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9632034-B2 | Fluorogenic and chromogenic substrate | LI-COR, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160266045-A1 | FLUOROGENIC AND CHROMOGENIC SUBSTRATE | LI-COR, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |