Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 8/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21497998 | 0.81 | NISCH (0.40) | KDM4EALDH1A1NISCH | |
| SCHEMBL20172203 | 0.79 | P2RX4 (0.37) | P2RX4SMN1; SMN2NISCHTP53 | |
| SCHEMBL31067286 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1P2RX4HPGDGLA | |
| SCHEMBL47007 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1P2RX4HPGDGLA | |
| Hydrogen Sulfide SCHEMBL28845788 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1P2RX4HPGDGLA | |
| SCHEMBL8101449 | 0.76 | MYC (0.40) | MYCGAASMN1; SMN2 | |
| SCHEMBL9102529 | 0.76 | LMNA (0.42) | ALDH1A1P2RX4SMN1; SMN2 | |
| SCHEMBL21691991 | 0.75 | P2RX4 (0.37) | ALDH1A1P2RX4HSD17B10RAB9ATP53 | |
| SCHEMBL22931992 | 0.75 | CYP1A2 (0.37) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL9100552 | 0.73 | KDM4E (0.39) | KDM4EALDH1A1P2RX4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282358-A | CYCLIZATION OF 2-HALOPHENOXYANILINES | CIBA-GEIGY CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |