SCHEMBL9105222

SCHEMBL9105222

CCC(N1c2ccc(C)cc2Sc2c(C)cccc21)S(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.31
HSD17B3 P37058 1/20 0.31
BCHE P06276 1/20 0.30
MAPT P10636 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100969 0.88 BCHE (0.38) BCHEMAPTMEN1KMT2APOLB
SCHEMBL9102414 0.86 BCHE (0.41) BCHEMAPTKMT2APOLB
SCHEMBL9099981 0.85 NR3C1 (0.33)
SCHEMBL9102550 0.82 BCHE (0.32) BCHEMAPTMEN1KMT2A
SCHEMBL9104043 0.82 HSD17B3 (0.31) HSD17B3BCHEMAPTKMT2ASMN1; SMN2
SCHEMBL9102087 0.81 BCHE (0.36) BCHEMAPTKMT2APOLB
SCHEMBL9104147 0.79 BCHE (0.41) BCHEMAPTKMT2APOLB
SCHEMBL9102163 0.79 RAD52 (0.32) MAPTSMN1; SMN2
SCHEMBL9100996 0.76 NR3C1 (0.33)
SCHEMBL9105686 0.76 MAPT (0.38) BCHEMAPTSMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed