Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23894744 | 0.89 | LMNA (0.57) | HSD17B10NPC1RAB9ASMN1; SMN2ELANE | |
| SCHEMBL8564239 | 0.86 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2ELANEKMT2A | |
| SCHEMBL40184 | 0.86 | HSD17B10 (0.88) | HSD17B10RAB9AELANEKMT2AMEN1 | |
| SCHEMBL9099319 | 0.85 | PARP10 (0.51) | HSD17B10NPC1RAB9ASMN1; SMN2ELANE | |
| Propane SCHEMBL28675522 | 0.84 | HSD17B10 (0.79) | HSD17B10NPC1RAB9ASMN1; SMN2ELANE | |
| Methane SCHEMBL7956977 | 0.84 | HSD17B10 (0.85) | HSD17B10RAB9AELANEKMT2AMEN1 | |
| SCHEMBL7026750 | 0.84 | HSD17B10 (0.85) | HSD17B10RAB9AELANEKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1374059 | 0.84 | HSD17B10 (0.85) | HSD17B10RAB9AELANEKMT2AMEN1 | |
| SCHEMBL12305405 | 0.83 | CALM1 (0.62) | SMN1; SMN2LMNAPOLBESR1 | |
| SCHEMBL8565931 | 0.83 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712388-A1 | USE OF PHENOLS AND PHENOL DERIVATES AS MEDICAMENTS WITH FIBRINOGEN-REDUCING EFFECT | Roche Diagnostics GmbH (DE) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995005358-A1 | USE OF PHENOLS AND PHENOL DERIVATES AS MEDICAMENTS WITH FIBRINOGEN-REDUCING EFFECT | BOEHRINGER MANNHEIM GMBH (DE) | 1995-02-23 | — | — | WO | disclosed |