SCHEMBL9103511

SCHEMBL9103511

CC(=O)c1ccc(C(=O)O)cc1.CC(=O)c1ccc(C)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.81
ALDH1A1 P00352 4/20 0.81
SRD5A2 P31213 3/20 0.71
MAPT P10636 4/20 0.63
NPC1 O15118 2/20 0.63
RAB9A P51151 2/20 0.63
MAPK1 P28482 1/20 0.63
STAT3 P40763 1/20 0.63
STAT1 P42224 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
TP53 P04637 1/20 0.57
TSHR P16473 1/20 0.57
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
LMNA P02545 2/20 0.54
RXRA P19793 1/20 0.52
RXRB P28702 1/20 0.52
MAOB P27338 1/20 0.52
HPGD P15428 3/20 0.50
AKR1C3 P42330 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzoic Acid SCHEMBL4131800 0.90 ALDH1A1 (0.90) SMN1; SMN2ALDH1A1SRD5A2MAPTTDP1
4-Methylbenzoic Acid SCHEMBL3175381 0.90 ALDH1A1 (0.90) SMN1; SMN2ALDH1A1SRD5A2MAPTTDP1
SCHEMBL211540 0.90 TSHR (0.71) SMN1; SMN2ALDH1A1SRD5A2MAPTRAB9A
SCHEMBL721041 0.90 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1SRD5A2MAPTNPC1
SCHEMBL55409 0.90 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1SRD5A2MAPTNPC1
Terephthalic Acid SCHEMBL526449 0.90 ALDH1A1 (1.00) SMN1; SMN2ALDH1A1SRD5A2TDP1TP53
Terephthalic Acid SCHEMBL15994097 0.90 ALDH1A1 (1.00) SMN1; SMN2ALDH1A1SRD5A2TDP1TP53
4-Methylbenzoic Acid SCHEMBL1331178 0.90 ALDH1A1 (1.00) SMN1; SMN2ALDH1A1SRD5A2TDP1TP53
4-Methylbenzoic Acid SCHEMBL93638 0.90 ALDH1A1 (1.00) SMN1; SMN2ALDH1A1SRD5A2TDP1TP53
4-Methylbenzoic Acid SCHEMBL11366477 0.90 ALDH1A1 (1.00) SMN1; SMN2ALDH1A1SRD5A2TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707656-A1 BIOTECHNOLOGICAL PROCESS FOR PRODUCING ALCOHOLS, ALDEHYDES AND CARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 1996-04-24 EP disclosed
WO-1995002061-A1 BIOTECHNOLOGICAL PROCESS FOR PRODUCING ALCOHOLS, ALDEHYDES AND CARBOXYLIC ACIDS BASF AKTIENGESELLSCHAFT (DE) 1995-01-19 WO disclosed