4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL93638

Cc1ccc(C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
SRD5A2 P31213 3/20 0.85
TSHR P16473 3/20 0.71
TP53 P04637 1/20 0.71
CES2 O00748 2/20 0.65
CES1 P23141 2/20 0.65
LMNA P02545 2/20 0.65
RXRA P19793 1/20 0.60
RXRB P28702 1/20 0.60
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzoic Acid SCHEMBL147465 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL11366477 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
Terephthalic Acid SCHEMBL526449 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
Terephthalic Acid SCHEMBL15994097 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1331178 1.00 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6113245 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6914468 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6112949 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL1042425 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53
4-Methylbenzoic Acid SCHEMBL6912547 0.97 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 32522 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079867-A Synthesis method of chiral delta-caprolactam compound 2026-05-26 CN claimed
CN-122060493-A Oil-soluble cerium oxide nanocluster with accurate structure and loadable and preparation method thereof 江苏科技大学 2026-05-19 CN claimed
CN-122036658-A Process for the synthesis of aromatic dicarboxylic acids 环球油品有限责任公司 2026-05-15 CN claimed
CN-224220794-U Recovery device of p-methylbenzoic acid 浙江东江绿色石化技术创新中心有限公司 2026-05-12 CN claimed
CN-122010721-A Hydrotreatment method of crude terephthalic acid 中国石油化工股份有限公司 2026-05-12 CN claimed
US-20260125368-A1 SALT OF GLP-1R AGONIST, PREPARATION METHOD THEREFOR AND USE THEREOF MINDRANK AI LTD (CN) 2026-05-07 US claimed
EP-4735459-A1 METHODS AND INTERMEDIATES FOR PREPARING ANTIVIRAL PRODRUGS GILEAD SCIENCES, INC. (US) 2026-05-06 EP claimed
EP-4288481-B1 PROCESS FOR MODIFYING AN AROMATIC POLYETHER BACKBONE AND A MODIFIED POLYETHER OBTAINED BY THIS PROCESS UNIV BERLIN TECH (DE) 2026-05-06 EP claimed
EP-4714955-A1 VERSATILE INTERMEDIATE FOR OPIOID DERIVATIVES, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shaoxing Zejun Pharmaceuticals Co., Ltd (CN) 2026-03-25 EP claimed
US-20260061413-A1 ANION EXCHANGE POLYMERS CAPABLE OF CONTROLLED CROSSLINKING UNIV DELAWARE (US) 2026-03-05 US claimed
US-3981831-A REACTION OF ORGANIC POLYISOCYANATE WITH ALKALI METAL SILICATE OR SILICA SOL BAYER AKTIENGESELLSCHAFT (DT) 1976-09-21 US claimed
US-3956168-A QUATERNARY AMMONIUM COMPOUND DAINIPPON INK AND CHEMICALS, INCORPORATED (JA) 1976-05-11 US claimed
US-3956362-A ESTERIFICATION HERCULES INCORPORATED (US) 1976-05-11 US claimed
US-3948968-A COMPLEXING WITH PYRIDINES OR QUINOLINES, REACTION WITH AMMONIA MARATHON OIL COMPANY (US) 1976-04-06 US claimed
US-3946067-A Process for the preparation of aromatic aldehydes NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1976-03-23 US claimed
US-3944598-A Production of amine salts of carboxylic acids THE LUMMUS COMPANY (US) 1976-03-16 US claimed
US-3944602-A PURIFICATION CHEMISCHE WERKE WITTEN GMBH (DT) 1976-03-16 US claimed
US-3943181-A Separating optically pure d-l-isomers of menthol, neomenthol and isomenthol HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 1976-03-09 US claimed
US-3935216-A Preparation of toluoyl-5-pyrryl-2-acetonitrile ETHYL CORPORATION (US) 1976-01-27 US claimed
US-3931305-A Terephthalic acid recovery by continuous flash crystallization STANDARD OIL COMPANY (US) 1976-01-06 US claimed