Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101226 | 0.92 | ABCB1 (0.47) | ABCB1NPC1RAB9A | |
| SCHEMBL2482845 | 0.81 | ABCB1 (0.51) | ABCB1NPC1RAB9A | |
| SCHEMBL17025770 | 0.80 | ABCB1 (0.40) | ABCB1LPAR1MEN1KMT2ARXFP1 | |
| SCHEMBL5064290 | 0.80 | ABCB1 (0.53) | ABCB1MEN1KMT2ARXFP1EED | |
| SCHEMBL17025742 | 0.79 | ABCB1 (0.39) | ABCB1LPAR1MEN1KMT2ARXFP1 | |
| SCHEMBL9232983 | 0.77 | ABCB1 (0.48) | ABCB1NPC1RAB9A | |
| SCHEMBL18091865 | 0.76 | NPC1 (0.48) | ABCB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17416629 | 0.75 | CTSD (0.43) | RXFP1KDM4ELMNANPC1RAB9A | |
| SCHEMBL9100311 | 0.75 | RAB9A (0.43) | ABCB1LMNAMAPTNPC1RAB9A | |
| SCHEMBL14688168 | 0.75 | ABCB1 (0.43) | ABCB1ALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2460786-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-06 | — | — | EP | disclosed |