Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 2/20 | 0.32 |
| ▸ | MC3R | P41968 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280399 | 0.91 | MAPT (0.37) | CDK4CCND1PIM1CYP3A4CYP2D6 | |
| SCHEMBL9105301 | 0.89 | TACR2 (0.42) | CDK4CCND1PIM1CYP3A4CYP2D6 | |
| SCHEMBL9107408 | 0.88 | LMNA (0.32) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL3700997 | 0.86 | APAF1 (0.38) | CDK4CCND1PIM1CYP3A4CYP2D6 | |
| SCHEMBL3691829 | 0.81 | HPGD (0.39) | CDK4CCND1PIM1CYP3A4CYP2D6 | |
| SCHEMBL3698794 | 0.81 | SMN1; SMN2 (0.42) | CYP3A4CYP2D6CYP2C9CYP2C19HPGD | |
| SCHEMBL9104168 | 0.80 | GPBAR1 (0.32) | KMT2A | |
| SCHEMBL9279133 | 0.80 | MAPT (0.39) | CDK4CCND1PIM1CYP3A4CYP2D6 | |
| SCHEMBL3702676 | 0.80 | DRD3 (0.37) | CDK4CCND1PIM1CYP3A4CYP2D6 | |
| SCHEMBL3775360 | 0.79 | APAF1 (0.40) | CDK4CCND1PIM1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460798-A2 | APAF-1 INHIBITOR COMPOUNDS | Laboratorios SALVAT, S.A. (ES) | 2012-06-06 | — | — | EP | disclosed |