Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HEXA | P06865 | 1/20 | 0.32 |
| ▸ | HEXB | P07686 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509399 | 0.80 | CYP1A2 (0.38) | TBXAS1ALDH1A1KMT2A | |
| SCHEMBL9099555 | 0.80 | CYP1A2 (0.38) | TBXAS1ALDH1A1KMT2A | |
| SCHEMBL8508167 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL8508170 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL8429544 | 0.66 | TDP1 (0.49) | ALDH1A1TDP1SMN1; SMN2LMNAGAA | |
| SCHEMBL8429546 | 0.66 | TDP1 (0.49) | ALDH1A1TDP1SMN1; SMN2LMNAGAA | |
| SCHEMBL952398 | 0.64 | TBXAS1 (0.35) | TBXAS1ALDH1A1 | |
| SCHEMBL952400 | 0.64 | TBXAS1 (0.35) | TBXAS1ALDH1A1 | |
| SCHEMBL17337617 | 0.64 | DGKA (0.47) | TBXAS1ALDH1A1KMT2ATDP1GAA | |
| SCHEMBL17337542 | 0.64 | ALDH1A1 (0.48) | PPARAPPARGALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040662-A2 | AMINOOXY-CONTAINING LINKER COMPOUNDS AND THEIR APPLICATION IN CONJUGATES | CELLPRO, INCORPORATED (US) | 1996-12-19 | — | — | WO | disclosed |