SCHEMBL9104043

SCHEMBL9104043

CCC(N1c2ccc(C)cc2Sc2ccc(C)cc21)S(=O)(=O)O

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.31
BCHE P06276 5/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
MAPT P10636 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ACHE P22303 1/20 0.30
POLB P06746 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9102414 0.91 BCHE (0.41) BCHECYP2D6TSHRCYP2C19MAPT
SCHEMBL9104147 0.91 BCHE (0.41) BCHECYP2D6TSHRCYP2C19MAPT
SCHEMBL9107461 0.85 NR3C1 (0.32)
SCHEMBL9102684 0.84 CYP2D6 (0.37) CYP2D6MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL9105222 0.82 DRD3 (0.31) HSD17B3BCHEMAPTSMN1; SMN2POLB
SCHEMBL9105616 0.82 BCHE (0.35) BCHECYP2D6TSHRCYP2C19MAPT
SCHEMBL9100349 0.81 METAP2 (0.31)
SCHEMBL9101691 0.80 METAP2 (0.33) BCHESMN1; SMN2
SCHEMBL6276192 0.79 BCHE (0.47) BCHECYP2D6TSHRCYP2C19MAPT
SCHEMBL9100922 0.78 BCHE (0.42) BCHECYP2D6TSHRCYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192948-B1 Chemifluorescent substrate for peroxide and peroxidase detection PIERCE BIOTECHNOLOGY, INC. (US) 2012-06-05 US disclosed
EP-0361470-B1 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO KK (JP) 1993-12-22 EP disclosed
US-5171668-A Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex FUJIREBIO INC. (JP) 1992-12-15 US disclosed
EP-0361470-A2 Method for the chemiluminescence assay of the activity of peroxidase FUJIREBIO INC. (JP) 1990-04-04 EP disclosed