Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099915 | 0.89 | PSEN1 (0.34) | ALDH1A1USP2LMNAMEN1KMT2A | |
| SCHEMBL9105568 | 0.88 | MDM2 (0.34) | ALDH1A1USP2NPSR1LMNAHTT | |
| SCHEMBL3713311 | 0.86 | PSEN1 (0.35) | ALDH1A1USP2NPSR1LMNAHTT | |
| SCHEMBL9281625 | 0.86 | MAPT (0.35) | ALDH1A1MEN1KMT2ATP53PSEN1 | |
| SCHEMBL9104196 | 0.83 | MDM2 (0.35) | ALDH1A1USP2NPSR1LMNAHTT | |
| SCHEMBL3693763 | 0.79 | TBXAS1 (0.40) | ALDH1A1USP2NPSR1LMNAHTT | |
| SCHEMBL3710700 | 0.78 | MDM2 (0.38) | ALDH1A1USP2TSHRMDM2TP53 | |
| SCHEMBL3701509 | 0.77 | KDM4E (0.40) | ALDH1A1MEN1KMT2AMDM2RXFP1 | |
| SCHEMBL3695334 | 0.77 | MDM2 (0.35) | ALDH1A1USP2NPSR1LMNAHTT | |
| SCHEMBL9107408 | 0.75 | LMNA (0.32) | ALDH1A1LMNAMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460798-A2 | APAF-1 INHIBITOR COMPOUNDS | Laboratorios SALVAT, S.A. (ES) | 2012-06-06 | — | — | EP | disclosed |