Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104196 | 0.89 | MDM2 (0.35) | MDM2ALDH1A1USP2NPSR1TSHR | |
| SCHEMBL9105301 | 0.89 | TACR2 (0.42) | TACR2HRH3MMP2MMP9 | |
| SCHEMBL9104517 | 0.88 | ALDH1A1 (0.35) | MDM2ALDH1A1USP2NPSR1TSHR | |
| SCHEMBL9107408 | 0.86 | LMNA (0.32) | ALDH1A1TP53LMNAKDM4E | |
| SCHEMBL3705051 | 0.84 | APAF1 (0.36) | MDM2ALDH1A1USP2NPSR1TSHR | |
| SCHEMBL3710700 | 0.83 | MDM2 (0.38) | MDM2ALDH1A1USP2TSHRTP53 | |
| SCHEMBL3701509 | 0.82 | KDM4E (0.40) | MDM2ALDH1A1PPARGNCOR2TACR2 | |
| SCHEMBL3695334 | 0.82 | MDM2 (0.35) | MDM2ALDH1A1USP2NPSR1TSHR | |
| SCHEMBL3697424 | 0.82 | APAF1 (0.34) | MDM2ALDH1A1USP2NPSR1TSHR | |
| SCHEMBL9101546 | 0.81 | C5AR1 (0.39) | ALDH1A1C5AR1TACR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460798-A2 | APAF-1 INHIBITOR COMPOUNDS | Laboratorios SALVAT, S.A. (ES) | 2012-06-06 | — | — | EP | disclosed |