SCHEMBL910456

SCHEMBL910456

Cl[Zr](Cl)C1C=C(Cc2ccccc2)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.39
PTPN1 P18031 1/20 0.37
CALM1 P0DP23 1/20 0.35
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910833 0.85 HTR6 (0.43) HTR6MAOAMAOBMAPT
SCHEMBL911338 0.80 HTR6 (0.33) HTR6
SCHEMBL911474 0.75 HTR6 (0.32) HTR6
SCHEMBL3678038 0.74 BCHE (0.38) HTR6PTPN1
SCHEMBL4083693 0.73 HTR6 (0.39) HTR6PTPN1CALM1MAOAMAOB
SCHEMBL4094363 0.73 HTR6 (0.39) HTR6PTPN1CALM1MAOAMAOB
SCHEMBL28843652 0.72 HTR6 (0.68) HTR6PTPN1CALM1MAOAMAOB
Hydrochloric Acid SCHEMBL910454 0.72 HTR6 (0.41) HTR6PTPN1CALM1MAOAMAOB
Hydrochloric Acid SCHEMBL4083691 0.72 HTR6 (0.41) HTR6PTPN1CALM1MAOAMAOB
Hydrochloric Acid SCHEMBL4094360 0.72 HTR6 (0.41) HTR6PTPN1CALM1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507604-B2 Polyolefin graft copolymer and adhesive composition IDEMITSU KOSAN CO., LTD. (JP) 2013-08-13 US disclosed
US-20110015338-A1 POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-01-20 US disclosed
US-20100324242-A1 HIGHLY PURE, TERMINAL-UNSATURATED OLEFIN POLYMER AND PROCESS FOR PRODUCTION THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2010-12-23 US disclosed
EP-2253648-A1 POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-11-24 EP disclosed
EP-2241582-A1 AQUEOUS DISPERSION CONTAINING POLYOLEFIN GRAFT COPOLYMER Idemitsu Kosan Co., Ltd. (JP) 2010-10-20 EP disclosed
WO-2009104782-A1 ETHYLENE HOMOPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104785-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104783-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed