SCHEMBL910833

SCHEMBL910833

Cl[Zr](Cl)C1C=C(CCc2ccccc2)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.43
PARK7 Q99497 1/20 0.38
S1PR1 P21453 1/20 0.33
S1PR5 Q9H228 1/20 0.33
MAOA P21397 3/20 0.32
MAOB P27338 3/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
CASP1 P29466 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KCNH2 Q12809 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
CYP2A6 P11509 1/20 0.31
HTR2A P28223 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
NR1H3 Q13133 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910456 0.85 HTR6 (0.39) HTR6MAOAMAOBMAPT
SCHEMBL3678038 0.79 BCHE (0.38) HTR6
SCHEMBL911338 0.75 HTR6 (0.33) HTR6
SCHEMBL911474 0.74 HTR6 (0.32) HTR6
Hydrochloric Acid SCHEMBL910832 0.73 HTR6 (0.46) HTR6PARK7MAOAMAOBALDH1A1
SCHEMBL8466396 0.70 HTR6 (0.41) HTR6PARK7
SCHEMBL911084 0.69 CYP2A6 (0.33) ALDH1A1CYP2A6
Hydrochloric Acid SCHEMBL8160756 0.67 HTR6 (0.43) HTR6PARK7S1PR1S1PR5ALDH1A1
SCHEMBL3192378 0.66 GPR3 (0.31)
SCHEMBL911104 0.65 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507604-B2 Polyolefin graft copolymer and adhesive composition IDEMITSU KOSAN CO., LTD. (JP) 2013-08-13 US disclosed
US-20110015338-A1 POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-01-20 US disclosed
US-20100324242-A1 HIGHLY PURE, TERMINAL-UNSATURATED OLEFIN POLYMER AND PROCESS FOR PRODUCTION THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2010-12-23 US disclosed
EP-2253648-A1 POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-11-24 EP disclosed