Hydrochloric Acid

Hydrochloric Acid

SCHEMBL910454

[Cl-].[Cl-].[Zr+2]C1C=C(Cc2ccccc2)c2ccccc21

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.41
PTPN1 P18031 1/20 0.39
CALM1 P0DP23 1/20 0.38
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
MAPT P10636 1/20 0.33
TEK Q02763 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
HTR2A P28223 1/20 0.31
SLC22A2 O15244 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL910832 0.84 HTR6 (0.46) HTR6MAOAMAOBMAPTHTR2A
Hydrochloric Acid SCHEMBL4083691 0.79 HTR6 (0.41) HTR6PTPN1CALM1MAOAMAOB
Hydrochloric Acid SCHEMBL4094360 0.79 HTR6 (0.41) HTR6PTPN1CALM1MAOAMAOB
Hydrochloric Acid SCHEMBL27520305 0.78 HTR6 (0.33) HTR6HTR2ASLC22A2
SCHEMBL27945125 0.76 HTR6 (0.42) HTR6PTPN1CALM1MAOAMAOB
SCHEMBL28843652 0.75 HTR6 (0.68) HTR6PTPN1CALM1MAOAMAOB
Hydrochloric Acid SCHEMBL28506062 0.75 HTR6 (0.38) HTR6HTR2A
Hydrochloric Acid SCHEMBL911472 0.74 HTR6 (0.33) HTR6
SCHEMBL910456 0.72 HTR6 (0.39) HTR6PTPN1CALM1MAOAMAOB
Hydrochloric Acid SCHEMBL3678035 0.72 ACHE (0.40) HTR6PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507604-B2 Polyolefin graft copolymer and adhesive composition IDEMITSU KOSAN CO., LTD. (JP) 2013-08-13 US disclosed
US-20110015338-A1 POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2011-01-20 US disclosed
US-20100324242-A1 HIGHLY PURE, TERMINAL-UNSATURATED OLEFIN POLYMER AND PROCESS FOR PRODUCTION THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2010-12-23 US disclosed
EP-2253648-A1 POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2010-11-24 EP disclosed
EP-2241582-A1 AQUEOUS DISPERSION CONTAINING POLYOLEFIN GRAFT COPOLYMER Idemitsu Kosan Co., Ltd. (JP) 2010-10-20 EP disclosed
WO-2009104782-A1 ETHYLENE HOMOPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104785-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104783-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed