Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121391 | 0.91 | LTA4H (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2120179 | 0.88 | NR5A1 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1958536 | 0.86 | NR5A1 (0.61) | LTA4HALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL3458574 | 0.86 | NR5A1 (0.61) | LTA4HALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL2119770 | 0.86 | NR5A1 (0.61) | LTA4HALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL54703 | 0.86 | NR5A1 (0.61) | LTA4HALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL2121574 | 0.86 | NR5A1 (0.61) | LTA4HALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL2119769 | 0.86 | NR5A1 (0.61) | LTA4HALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL1960613 | 0.86 | NR5A1 (0.61) | LTA4HALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL1960170 | 0.86 | NR5A1 (0.61) | LTA4HALDH1A1NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965591-A | MONOAMINE OXIDASE INHIBITOR; FOR PROPHYLAXIS AND TREATING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 1999-10-12 | — | — | US | claimed |
| US-20240156788-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | NORTH CAROLINA STATE UNIVERSITY | 2024-05-16 | — | — | US | disclosed |
| US-11883384-B2 | Substituted 2-aminobenzimidazoles analogs as antibiofilm agents | OHIO STATE INNOVATION FOUNDATION (US) | 2024-01-30 | — | — | US | disclosed |
| US-20230138583-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION | 2023-05-04 | — | — | US | disclosed |
| EP-3774740-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | Ohio State Innovation Foundation (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-112351973-A | Substituted 2-aminobenzimidazole analogs as anti-biofilm agents | 俄亥俄州国家创新基金会 | 2021-02-09 | — | — | CN | disclosed |
| US-20210023060-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | NORTH CAROLINA STATE UNIVERSITY | 2021-01-28 | — | — | US | disclosed |
| WO-2019195493-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |
| US-9955689-B2 | Method for promoting plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-01 | — | — | US | disclosed |
| US-9894901-B2 | Method for promoting plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-20 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0168607-B1 | PYRROLIDINE-CARBOXYLIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| EP-0168607-A1 | Pyrrolidine-carboxylic-acid derivatives, process for their preparation | BASF Aktiengesellschaft (DE) | 1986-01-22 | — | — | EP | disclosed |
| US-4438277-A | Hydronaphthalene derivatives | SANKYO COMPANY, LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| US-4361515-A | Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1982-11-30 | — | — | US | disclosed |
| US-4246405-A | Method for preparation of β-lactam compound | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210023060-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | ITGB3, ITGB2, ITGAM | CA12 4414/4885CA1 4782/4885CA2 3406/4885 |
| US-20230138583-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | ITGB3, ITGB2, ITGAM | CA12 4414/4885CA1 4782/4885CA2 3406/4885 |
| US-11883384-B2 | Substituted 2-aminobenzimidazoles analogs as antibiofilm agents | ITGB3, ITGB2, ITGAM | CA12 4414/4885CA1 4782/4885CA2 3406/4885 |
| US-20240156788-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | ITGB3, ITGB2, ITGAM | CA12 4414/4885CA1 4782/4885CA2 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.