Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345872 | 0.81 | SLC15A1 (0.44) | SLC15A1CSNK1EEPHX1CPA1ALPI | |
| SCHEMBL10622532 | 0.79 | EPHX1 (0.48) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL6556276 | 0.79 | EPHX1 (0.48) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL7418519 | 0.78 | SLC15A1 (0.42) | SLC15A1CSNK1EEPHX1CPA1ALPI | |
| SCHEMBL7418523 | 0.78 | SLC15A1 (0.42) | SLC15A1CSNK1EEPHX1CPA1ALPI | |
| Hydrochloric Acid SCHEMBL5711578 | 0.77 | EPHX1 (0.47) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL7337442 | 0.74 | KDM4E (0.49) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL7275924 | 0.74 | KDM4E (0.49) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL7340521 | 0.74 | GBA1 (0.39) | TACR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6351074 | 0.73 | SLC15A1 (0.43) | SLC15A1CSNK1EEPHX1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554783-A | (2R, 3R, 4S, 5S)-3-ACETOXY-2,5-BIS/BENZYLOXYCARBONYLAMINO/ -4-BROMO-1,5-DIPHENYLHEXANE | ABBOTT LABORATORIES (US) | 1996-09-10 | — | — | US | disclosed |