Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 7/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1226524 | 0.77 | KDM4E (0.37) | WNT3ATNKS2KDM4E | |
| SCHEMBL6455478 | 0.77 | KDM4E (0.60) | KDM4ETUBB3ALDH1A1ADRB2NOS3 | |
| SCHEMBL6415688 | 0.74 | TNKS2 (0.42) | WNT3ATNKS2KDM4ECYP2C19 | |
| SCHEMBL6420412 | 0.74 | KDM4E (0.35) | WNT3ATNKS2KDM4EALDH1A1CYP2C19 | |
| SCHEMBL9105995 | 0.73 | KDM4E (0.36) | WNT3ATNKS2KDM4ECYP2C19HRH4 | |
| SCHEMBL31031407 | 0.71 | WNT3A (0.38) | WNT3ATNKS2 | |
| SCHEMBL606802 | 0.69 | HRH4 (0.47) | CYP2C19HRH4HRH2HRH3 | |
| SCHEMBL9583264 | 0.67 | ACHE (0.67) | KDM4EALDH1A1CYP2C19 | |
| SCHEMBL603795 | 0.67 | HRH4 (0.42) | CYP2C19HRH4HRH3 | |
| SCHEMBL21507300 | 0.66 | TLR8 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459197-A1 | COMPOUNDS FOR THE REDUCTION OF -AMYLOID PRODUCTION | Bristol-Myers Squibb Company (US) | 2012-06-06 | — | — | EP | claimed |