Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285612 | 0.84 | MAPK1 (0.52) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL2783060 | 0.82 | ALDH1A1 (0.54) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL9107325 | 0.81 | MAPK1 (0.61) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL6579407 | 0.80 | CFTR (0.63) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL5717623 | 0.80 | ALDH1A1 (0.67) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL9103612 | 0.79 | MAPK1 (0.62) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL8861179 | 0.79 | ALDH1A1 (0.70) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL28458600 | 0.78 | KDM4E (0.57) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28714809 | 0.75 | TP53 (0.46) | MAPK1CASP1CASP7ALDH1A1MAPT | |
| SCHEMBL7416308 | 0.74 | ALDH1A1 (0.60) | MAPK1CASP1CASP7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2174934-B1 | OXOPYRAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2012-06-06 | — | — | EP | disclosed |
| CN-101778832-A | Oxopyrazine derivative and weedicide | KUMIAI CHEMICAL INDUSTRY CO | 2010-07-14 | — | — | CN | disclosed |