Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861179 | 0.87 | ALDH1A1 (0.70) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL5717810 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL9107325 | 0.84 | MAPK1 (0.61) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL6579407 | 0.82 | CFTR (0.63) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL7416308 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL9103612 | 0.81 | MAPK1 (0.62) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL6529612 | 0.80 | CASP1 (0.60) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL9106035 | 0.80 | MAPK1 (0.57) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL1963617 | 0.79 | CFTR (0.68) | ALDH1A1MAPTCYP2C9CYP2C19HTT | |
| SCHEMBL1122732 | 0.79 | KDM4E (0.62) | ALDH1A1MAPTCYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| CN-1492874-A | Macrolide antibiotics | — | 2004-04-28 | — | — | CN | disclosed |