SCHEMBL9106810

SCHEMBL9106810

COP(=O)(CCc1ccccn1)OC

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.51
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
ALOX15 P16050 1/20 0.50
TDP1 Q9NUW8 1/20 0.47
HRH1 P35367 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
FDPS P14324 2/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KCNA5 P22460 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769097 0.83 HRH3 (0.49) HRH3ALDH1A1LMNATAAR1ALOX15
SCHEMBL2955427 0.83 HRH3 (0.49) HRH3ALDH1A1LMNATAAR1ALOX15
SCHEMBL27952913 0.77 CA12 (0.45) HRH3ALDH1A1LMNATAAR1ALOX15
SCHEMBL932969 0.77 FDPS (0.61) HRH3ALDH1A1LMNATAAR1ALOX15
Metyridine SCHEMBL167318 0.76 HRH1 (0.55) HRH3ALDH1A1LMNATAAR1ALOX15
Metyridine SCHEMBL30481621 0.76 HRH1 (0.55) HRH3ALDH1A1LMNATAAR1ALOX15
SCHEMBL9338333 0.74 LMNA (0.47) HRH3ALDH1A1LMNATAAR1ALOX15
SCHEMBL27563232 0.74 HRH3 (0.46) HRH3ALDH1A1LMNATAAR1ALOX15
SCHEMBL7096844 0.73 KDM1A (0.35) ALDH1A1
SCHEMBL28182883 0.73 HPGD (0.46) HRH3ALDH1A1LMNATAAR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639199-A1 PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS. DU PONT (US) 1995-02-22 EP disclosed
EP-0639199-A4 PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS. DU PONT (US) 1993-09-17 EP disclosed
WO-1992012985-A1 PREPARATION OF 2-(PYRIDYL)ETHYL SUBSTITUTED PHOSPHORUS COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-06 WO disclosed