Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413523 | 0.89 | TSHR (0.46) | ALDH1A1TSHRHSD17B10TDP1EPHX2 | |
| SCHEMBL9015649 | 0.88 | TSHR (0.37) | ALDH1A1TP53TSHRHSD17B10TDP1 | |
| SCHEMBL1326440 | 0.85 | TSHR (0.40) | ALDH1A1TSHRHSD17B10TDP1EPHX2 | |
| SCHEMBL9149195 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TP53TSHR | |
| SCHEMBL28325994 | 0.83 | DGKA (0.40) | ALDH1A1TSHRHSD17B10TDP1EPHX2 | |
| SCHEMBL2399659 | 0.83 | DGKA (0.40) | ALDH1A1TSHRHSD17B10TDP1EPHX2 | |
| SCHEMBL11420930 | 0.83 | DGKA (0.40) | ALDH1A1TSHRHSD17B10TDP1EPHX2 | |
| SCHEMBL30503209 | 0.82 | EPHX2 (0.40) | ALDH1A1TSHRHSD17B10TDP1EPHX2 | |
| SCHEMBL2080938 | 0.82 | TSHR (0.62) | ALDH1A1TSHRHSD17B10EPHX2 | |
| SCHEMBL28389672 | 0.82 | TSHR (0.54) | ALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451654-A | Addition polymerization catalyst | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5387654-A | Hydroxy-peroxides and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0381135-B1 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5304649-A | Curing agent for unsaturated polyesters | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0381135-A2 | Novel hydroxy-peroxides and their uses | ATOCHEM NORTH AMERICA, INC. (US) | 1990-08-08 | — | — | EP | disclosed |