Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694489 | 0.78 | NPC1 (0.41) | TP53NPC1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL7359011 | 0.76 | CYP17A1 (0.42) | CYP17A1SMN1; SMN2TSHROPRD1KDM4E | |
| SCHEMBL10399939 | 0.76 | CYP17A1 (0.42) | CYP17A1SMN1; SMN2KDM4EBRD4SLC6A2 | |
| SCHEMBL27551098 | 0.70 | NPC1 (0.46) | TP53NPC1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL18010784 | 0.68 | ALDH1A1 (0.43) | TP53NPC1SMN1; SMN2TSHROPRD1 | |
| SCHEMBL170176 | 0.66 | KDM4E (0.52) | TP53NPC1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL1445518 | 0.65 | SMN1; SMN2 (0.47) | TP53NPC1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL10684552 | 0.65 | SLC6A2 (0.35) | CYP17A1TSHRLMNASLC6A2SLC6A4 | |
| SCHEMBL1445699 | 0.64 | KDM4E (0.50) | TP53NPC1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL14465345 | 0.64 | NPC1 (0.60) | TP53NPC1SMN1; SMN2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180822-A | Highly selective chelating resins and monomers for their preparation | REILLY INDUSTRIES, INC. (US) | 1993-01-19 | — | — | US | claimed |
| US-5444137-A | Highly selective chelating resins and monomers for their preparation | REILLY INDUSTRIES, INC. (US) | 1995-08-22 | — | — | US | disclosed |
| US-5180822-A | Highly selective chelating resins and monomers for their preparation | REILLY INDUSTRIES, INC. (US) | 1993-01-19 | — | — | US | disclosed |