Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CX3CR1 | P49238 | 19/20 | 0.65 |
| ▸ | CXCR2 | P25025 | 18/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214656 | 0.91 | CXCR2 (0.79) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL1872128 | 0.88 | CX3CR1 (0.77) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL1589096 | 0.88 | CX3CR1 (0.77) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL9106210 | 0.88 | CX3CR1 (0.80) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL214430 | 0.80 | CXCR2 (0.64) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL20455391 | 0.79 | CX3CR1 (1.00) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL31199186 | 0.79 | CX3CR1 (1.00) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL18312509 | 0.79 | CX3CR1 (1.00) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL215431 | 0.79 | CX3CR1 (1.00) | CX3CR1CXCR2ADORA1 | |
| SCHEMBL212589 | 0.79 | CXCR2 (0.62) | CX3CR1CXCR2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435993-B2 | Methods of inhibiting metastasis from cancer | PHILADELPHIA HEALTH AND EDUCATION CORPORATION (US) | 2013-05-07 | — | — | US | disclosed |
| US-20120141471-A1 | Methods of Inhibiting Metastasis from Cancer | Alliance Discovery, Inc. | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120141471-A1 | Methods of Inhibiting Metastasis from Cancer | CX3CR1, CXCR3, CCR5 | CX3CR1 1/4885CXCR2 7/4885ADORA1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.