SCHEMBL9109464

SCHEMBL9109464

[NH]C(=O)CC=CCCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 18/20 0.54
TOP1 P11387 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9109458 1.00 GPR52 (0.54) GPR52TOP1
SCHEMBL6971097 0.85 GPR52 (0.58) GPR52
SCHEMBL6971091 0.83 GPR52 (0.56) GPR52
SCHEMBL9109471 0.81 GPR52 (0.54) GPR52
SCHEMBL2780407 0.81 GPR52 (0.50) GPR52
SCHEMBL7762166 0.79 GPR52 (0.57) GPR52
SCHEMBL9715286 0.79 GPR52 (0.57) GPR52
SCHEMBL7762164 0.79 GPR52 (0.57) GPR52
SCHEMBL9114898 0.79 GPR52 (0.66) GPR52
SCHEMBL9114906 0.79 GPR52 (0.66) GPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1114834-A antidiabetic agent OTSUKA PHARMA CO LTD (JP) 1996-01-10 CN disclosed
EP-0670831-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-09-13 EP disclosed
WO-1995009159-A1 QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-04-06 WO disclosed