Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 15/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109458 | 0.81 | GPR52 (0.54) | GPR52 | |
| SCHEMBL9109464 | 0.81 | GPR52 (0.54) | GPR52 | |
| SCHEMBL6971097 | 0.80 | GPR52 (0.58) | GPR52HDAC2HDAC8HDAC6 | |
| SCHEMBL6971091 | 0.79 | GPR52 (0.56) | GPR52 | |
| SCHEMBL9109471 | 0.77 | GPR52 (0.54) | GPR52HDAC2HDAC8HDAC6 | |
| SCHEMBL7762166 | 0.75 | GPR52 (0.57) | GPR52 | |
| SCHEMBL9715286 | 0.75 | GPR52 (0.57) | GPR52 | |
| SCHEMBL7762164 | 0.75 | GPR52 (0.57) | GPR52 | |
| SCHEMBL7085533 | 0.74 | MAOB (0.67) | HDAC2HDAC8HDAC6 | |
| SCHEMBL6758436 | 0.73 | KEAP1 (0.63) | GPR52HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167458-A1 | CHIRAL DIACHYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | Intrexon Corporation (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008153801-A1 | CHIRAL DIACHYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | INTREXON CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |