SCHEMBL912657

SCHEMBL912657

COc1ccc(C(OC[C@@H]2O[C@H](n3ccc(=O)[nH]c3=O)CC2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DUT P33316 5/20 0.60
TYMP P19971 2/20 0.52
TYMS P04818 5/20 0.49
P2RY14 Q15391 1/20 0.42
P2RY2 P41231 1/20 0.41
P2RY4 P51582 1/20 0.41
P2RY6 Q15077 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL912656 1.00 DUT (0.60) DUTTYMPTYMSP2RY14P2RY2
SCHEMBL14403996 1.00 DUT (0.60) DUTTYMPTYMSP2RY14P2RY2
SCHEMBL19841219 1.00 DUT (0.60) DUTTYMPTYMSP2RY14P2RY2
SCHEMBL13444851 1.00 DUT (0.60) DUTTYMPTYMSP2RY14P2RY2
SCHEMBL13463839 1.00 DUT (0.60) DUTTYMPTYMSP2RY14P2RY2
SCHEMBL4422700 0.93 DUT (0.68) DUTTYMPTYMSP2RY2P2RY4
SCHEMBL3492644 0.93 DUT (0.68) DUTTYMPTYMSP2RY2P2RY4
SCHEMBL3576747 0.93 DUT (0.68) DUTTYMPTYMSP2RY2P2RY4
SCHEMBL10446526 0.93 DUT (0.68) DUTTYMPTYMSP2RY2P2RY4
SCHEMBL10446525 0.93 DUT (0.68) DUTTYMPTYMSP2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 US disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 EP disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 EP disclosed
US-20210403978-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-30 US disclosed
US-11149296-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-10-19 US disclosed
US-20200232005-A1 Methods of Producing and Using Single-Stranded Deoxyribonucleic Acids and Compositions for Use in Practicing the Same TAKARA BIO USA, INC. 2020-07-23 US disclosed
US-10584363-B2 Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same TAKARA BIO USA, INC. (US) 2020-03-10 US disclosed
US-20180100181-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-04-12 US disclosed
US-20170349927-A1 METHODS OF PRODUCING AND USING SINGLE-STRANDED DEOXYRIBONUCLEIC ACIDS AND COMPOSITIONS FOR USE IN PRACTICING THE SAME TAKARA BIO USA, INC. 2017-12-07 US disclosed
US-8017620-B2 Dutpase inhibitors MEDIVIR AB (SE) 2011-09-13 US disclosed
EP-1308452-B1 Oligonucleotide labeling reactants based on acyclonucleosides and conjugates derived thereof WALLAC OY (FI) 2008-03-19 EP disclosed
US-7282581-B2 Oligonucleotide labeling reactants based on acyclonucleosides and conjugates derived thereof WALLAC OY (FI) 2007-10-16 US disclosed
EP-1701727-A1 DUTPASE INHIBITORS Medivir Aktiebolag (SE) 2006-09-20 EP disclosed
US-6949639-B1 Oligonucleotide labeling reactants and their use WALLAC OY (FI) 2005-09-27 US disclosed
WO-2005085861-A2 NUCLEIC ACIDS AND ENCODED POLYPEPTIDES FOR USE IN LIVER DISORDERS AND EPITHELIAL CANCER ORIDIS BIOMED FORSCHUNGS- UND ENTWICKLUNGS GMBH (AT) 2005-09-15 WO disclosed
WO-2005065689-A1 DUTPASE INHIBITORS MEDIVIR AB (SE) 2005-07-21 WO disclosed
US-20040260080-A1 Oligonucleotide labeling reactants and their use HOVINEN JARI (FI) 2004-12-23 US disclosed
US-20030118999-A1 Oligonucleotide labeling reactants based on acyclonucleosides and conjugates derived thereof WALLAC OY (FI) 2003-06-26 US disclosed
EP-1308452-A2 Oligonucleotide labeling reactants based on acyclonucleosides and conjugates derived thereof WALLAC OY (FI) 2003-05-07 EP disclosed
EP-1152010-A2 Oligonucleotide labeling reactants and their use WALLAC OY (FI) 2001-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040260080-A1 Oligonucleotide labeling reactants and their use SSU72, LIG4, NSUN2 DUT 15/4885TYMP 1443/4885TYMS 867/4885
US-20030118999-A1 Oligonucleotide labeling reactants based on acyclonucleosides and conjugates derived thereof PCNA, DUT, POLL DUT 2/4885TYMP 79/4885TYMS 107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.