Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104627 | 0.85 | KMT2A (0.48) | KMT2ATDP1KDM3BALDH1A1MEN1 | |
| SCHEMBL1227831 | 0.76 | KMT2A (0.62) | KMT2ATDP1KDM3BALDH1A1MEN1 | |
| 5-Bromouracil SCHEMBL639925 | 0.74 | KMT2A (0.39) | KMT2ATDP1KDM3BALDH1A1MEN1 | |
| SCHEMBL3537530 | 0.74 | KMT2A (0.51) | KMT2ATDP1KDM3BALDH1A1MEN1 | |
| SCHEMBL9108064 | 0.72 | KMT2A (0.57) | KMT2ATDP1KDM3BALDH1A1MEN1 | |
| SCHEMBL21345745 | 0.70 | KMT2A (0.54) | KMT2ATDP1KDM3BALDH1A1MEN1 | |
| SCHEMBL18653592 | 0.69 | KMT2A (0.37) | KMT2ATDP1KDM3B | |
| SCHEMBL11458310 | 0.69 | DAO (0.50) | KMT2ATDP1KDM3BALDH1A1MEN1 | |
| SCHEMBL101944 | 0.69 | LMNA (0.41) | GAA | |
| SCHEMBL18640323 | 0.68 | KMT2A (0.60) | KMT2ATDP1KDM3BMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558634-A4 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES INC (US) | 1995-06-28 | — | — | EP | disclosed |
| EP-0558634-A1 | TRIPLEX-FORMING OLIGOMERS CONTAINING MODIFIED BASES | GILEAD SCIENCES, INC. (US) | 1993-09-08 | — | — | EP | disclosed |