Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109802 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL12549306 | 0.84 | POLB (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL1667029 | 0.83 | TP53 (0.57) | PLA2G4B | |
| SCHEMBL1667028 | 0.83 | TP53 (0.57) | PLA2G4B | |
| SCHEMBL1931432 | 0.83 | THRB (0.56) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL1931433 | 0.83 | THRB (0.56) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL11366685 | 0.82 | MAOB (0.46) | ALDH1A1MAOBCYP2C19TDP1 | |
| SCHEMBL9112220 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAOBCYP2C19PARP10 | |
| SCHEMBL9112229 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAOBCYP2C19PARP10 | |
| SCHEMBL9696619 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAOBTDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460810-B1 | NOVEL FLAVANONE DERIVATIVE | UNIV OKAYAMA NAT UNIV CORP (JP) | 2015-07-15 | — | — | EP | disclosed |
| CN-104285179-A | Particles for electrophoretic displays | MERCK PATENT GMBH | 2015-01-14 | — | — | CN | disclosed |
| US-8916526-B2 | Flavanone derivative | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20120202980-A1 | Novel Flavanone Derivative | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2012-08-09 | — | — | US | disclosed |
| EP-2460810-A1 | NOVEL FLAVANONE DERIVATIVE | National University Corporation Okayama University (JP) | 2012-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202980-A1 | Novel Flavanone Derivative | GALE, VRK1, GALK1 | ALDH1A1 817/4885MAPT 4011/4885SMN1; SMN2 3909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.