Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530565 | 0.83 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1L3MBTL1HPGD | |
| SCHEMBL9107032 | 0.80 | HDAC3 (0.65) | RAB9ANPC1L3MBTL1HDAC3ALOX12 | |
| SCHEMBL27345911 | 0.79 | HDAC3 (1.00) | SMN1; SMN2RAB9ANPC1HDAC3KMT2A | |
| SCHEMBL27996731 | 0.79 | SMN1; SMN2 (0.73) | SMN1; SMN2RAB9ANPC1L3MBTL1HPGD | |
| SCHEMBL27804343 | 0.79 | CA12 (0.55) | SMN1; SMN2RAB9ANPC1L3MBTL1HDAC3 | |
| SCHEMBL4254670 | 0.78 | HDAC3 (0.91) | SMN1; SMN2RAB9ANPC1HDAC3KMT2A | |
| SCHEMBL28607364 | 0.75 | RAB9A (0.69) | SMN1; SMN2RAB9ANPC1L3MBTL1HPGD | |
| SCHEMBL8652161 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2RAB9ANPC1L3MBTL1HPGD | |
| SCHEMBL425836 | 0.74 | ALDH1A1 (0.53) | SMN1; SMN2RAB9ANPC1HPGDHDAC3 | |
| SCHEMBL6771010 | 0.73 | HPGD (0.65) | SMN1; SMN2RAB9ANPC1L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631571-A1 | PREPARATION OF OPTICALLY ACTIVE HYDRAZINES AND AMINES. | DU PONT (US) | 1995-01-04 | — | — | EP | disclosed |