Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 15/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110385 | 0.84 | MAPT (0.53) | NPSR1MAPTHTT | |
| SCHEMBL2306805 | 0.77 | TXNRD1 (0.54) | TXNRD1NPSR1S1PR4MAPTS1PR1 | |
| SCHEMBL13728591 | 0.76 | TXNRD1 (0.46) | TXNRD1NPSR1S1PR4MAPTS1PR1 | |
| SCHEMBL21492056 | 0.75 | PIN1 (0.49) | NPSR1 | |
| SCHEMBL4311846 | 0.75 | TXNRD1 (0.48) | TXNRD1NPSR1S1PR4MAPTS1PR1 | |
| SCHEMBL4305170 | 0.75 | TXNRD1 (0.56) | TXNRD1NPSR1S1PR4MAPTS1PR1 | |
| SCHEMBL4308799 | 0.75 | MAPT (0.65) | TXNRD1NPSR1S1PR4MAPTS1PR1 | |
| SCHEMBL3403683 | 0.74 | TXNRD1 (0.57) | TXNRD1NPSR1S1PR4MAPTS1PR1 | |
| SCHEMBL28489675 | 0.73 | TXNRD1 (0.57) | TXNRD1NPSR1S1PR4MAPTS1PR1 | |
| SCHEMBL27218067 | 0.73 | TXNRD1 (0.57) | TXNRD1NPSR1S1PR4MAPTS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |