Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110118 | 0.84 | TXNRD1 (0.46) | MAPTHTTNPSR1 | |
| SCHEMBL21522837 | 0.82 | MAPT (0.55) | MAPTHTTMERTKNPSR1FGFR4 | |
| SCHEMBL21492056 | 0.81 | PIN1 (0.49) | NPSR1CYP2C19POLBCNR2LATS1 | |
| SCHEMBL31515714 | 0.79 | MAPT (0.59) | MAPTHTTMERTKFGFR4RPS6KB2 | |
| SCHEMBL3486254 | 0.77 | MAPT (0.57) | MAPTHTTMERTKNPSR1FGFR4 | |
| SCHEMBL10697630 | 0.76 | MAPT (0.55) | MAPTHTTMERTKNPSR1FGFR4 | |
| SCHEMBL10697343 | 0.75 | MAPT (0.73) | MAPTHTTMERTKFGFR4RPS6KB2 | |
| SCHEMBL8882680 | 0.75 | L3MBTL1 (0.48) | MAPTHTTNPSR1TDP1L3MBTL1 | |
| SCHEMBL5099519 | 0.75 | MAPT (0.61) | MAPTHTTMERTKNPSR1FGFR4 | |
| SCHEMBL9110706 | 0.74 | MAPT (0.65) | MAPTHTTMERTKFGFR4RPS6KB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |