SCHEMBL9110635

SCHEMBL9110635

Cc1cc(-c2ccccc2)cc(C)c1C1=C(OC(=O)C(C)(C)C)C2C3CCC(O3)C2C1=O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.33
ELANE P08246 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CNR1 P21554 2/20 0.32
CNR2 P34972 2/20 0.32
ALDH1A1 P00352 1/20 0.31
OXTR P30559 1/20 0.30
AVPR1A P37288 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6727746 1.00 L3MBTL1 (0.33) L3MBTL1ELANELMNAMAPTNPSR1
SCHEMBL18873778 1.00 L3MBTL1 (0.33) L3MBTL1ELANELMNAMAPTNPSR1
SCHEMBL18873832 0.89
SCHEMBL10225714 0.89
SCHEMBL6727555 0.89 L3MBTL1 (0.35) L3MBTL1LMNAMAPTCNR1CNR2
SCHEMBL18874243 0.89 L3MBTL1 (0.35) L3MBTL1LMNAMAPTCNR1CNR2
SCHEMBL2124181 0.87 ELANE (0.34) ELANE
SCHEMBL10257612 0.87 ELANE (0.34) ELANE
SCHEMBL6727914 0.86 SLC6A3 (0.32) L3MBTL1LMNAALDH1A1
SCHEMBL10187550 0.86 ELANE (0.31) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2173755-B1 NOVEL HERBICIDES SYNGENTA LTD (GB) 2017-05-17 EP disclosed
US-8940913-B2 Herbicides SYNGENTA CROP PROTECTION, LLC (US) 2015-01-27 US disclosed
US-20120142529-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142529-A1 NOVEL HERBICIDES DDT, CYP4X1, CYP1B1 L3MBTL1 1453/4885ELANE 4611/4885LMNA 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.