Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837897 | 0.81 | KMT2A (0.55) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL16563162 | 0.79 | LMNA (0.73) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL17847051 | 0.75 | POLB (0.53) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL2711475 | 0.73 | ALDH1A1 (0.58) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15557817 | 0.71 | ALDH1A1 (0.49) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL23152264 | 0.71 | HTT (0.53) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15709862 | 0.71 | LMNA (0.61) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL31403253 | 0.71 | TDP1 (0.49) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL12646511 | 0.71 | LMNA (0.55) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL28653273 | 0.70 | ALDH1A1 (0.59) | LMNAKMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |