Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857527 | 0.74 | GPR3 (0.38) | GPR3MEN1POLBKMT2AATM | |
| SCHEMBL7542082 | 0.74 | GPR3 (0.33) | GPR3 | |
| SCHEMBL29979921 | 0.74 | GPR3 (0.33) | GPR3 | |
| Hydrochloric Acid SCHEMBL911069 | 0.74 | GPR3 (0.35) | GPR3MEN1POLBKMT2A | |
| SCHEMBL6129625 | 0.73 | HTR6 (0.39) | GPR3 | |
| Hydrochloric Acid SCHEMBL4430821 | 0.73 | PTPN1 (0.40) | GPR3MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL6903195 | 0.73 | GAA (0.30) | GAA | |
| Hydrochloric Acid SCHEMBL911472 | 0.73 | HTR6 (0.33) | — | |
| SCHEMBL5702787 | 0.72 | GPR3 (0.31) | GPR3 | |
| SCHEMBL5205595 | 0.72 | JAK2 (0.33) | GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1674483-B1 | HIGHER OLEFIN POLYMER HAVING POLAR GROUP AND PROCESS FOR PRODUCING THE SAME | IDEMITSU KOSAN CO (JP) | 2015-03-25 | — | — | EP | disclosed |
| US-8507604-B2 | Polyolefin graft copolymer and adhesive composition | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| EP-1867662-B2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-7981959-B2 | Resin composition, process for producing the same and molding of the resin composition | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20110015338-A1 | POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20100324242-A1 | HIGHLY PURE, TERMINAL-UNSATURATED OLEFIN POLYMER AND PROCESS FOR PRODUCTION THEREOF | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2253648-A1 | POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION | Idemitsu Kosan Co., Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| EP-1867662-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| EP-1865006-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| US-20090076195-A1 | RESIN COMPOSITION, PROCESS FOR PRODUCING THE SAME AND MOLDING OF THE RESIN COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
| EP-1865006-A2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | Idemitsu Kosan Co., Ltd. (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1674483-A1 | HIGHER OLEFIN POLYMER HAVING POLAR GROUP AND PROCESS FOR PRODUCING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2006-06-28 | — | — | EP | disclosed |
| US-5968863-A | REACTION OF LIGAND WITH DOUBLE ANION FOR POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1999-10-19 | — | — | US | disclosed |