Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL4080901 | 0.88 | SLC34A1 (0.44) | BBOX1MMP1MMP2SLC34A1 | |
| Phosphoric Acid SCHEMBL19812287 | 0.81 | LMNA (0.39) | BBOX1LMNAESR1ADORA3CDC25A | |
| Phosphoric Acid SCHEMBL19811631 | 0.79 | BBOX1 (0.41) | BBOX1LMNAESR1ADORA3CDC25A | |
| Phosphoric Acid SCHEMBL14125641 | 0.78 | LMNA (0.40) | BBOX1LMNAESR1ADORA3CDC25A | |
| SCHEMBL239012 | 0.77 | — | — | |
| Phosphoric Acid SCHEMBL29166204 | 0.75 | BBOX1 (0.42) | BBOX1LMNAESR1ADORA3CDC25A | |
| Tetrylammonium SCHEMBL7131133 | 0.75 | TSHR (0.53) | LMNAESR1ADORA3CDC25AAGTR1 | |
| Phosphoric Acid SCHEMBL4405667 | 0.75 | BBOX1 (0.42) | BBOX1LMNAESR1ADORA3CDC25A | |
| Hydrochloric Acid SCHEMBL905740 | 0.73 | — | — | |
| Water SCHEMBL5381081 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653974-A1 | METHOD OF MAKING A COATED ABRASIVE ARTICLE CONTAINING A CONDUCTIVE BACKING. | MINNESOTA MINING & MFG (US) | 1995-05-24 | — | — | EP | disclosed |
| US-5328716-A | Antistatic agents for abrasives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| WO-1994004317-A1 | METHOD OF MAKING A COATED ABRASIVE ARTICLE CONTAINING A CONDUCTIVE BACKING | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |