Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990744 | 0.93 | GHSR (0.43) | GHSRHDAC1HDAC7KCNA3TACR1 | |
| SCHEMBL8990737 | 0.93 | GHSR (0.43) | GHSRHDAC1HDAC7KCNA3TACR1 | |
| SCHEMBL8990912 | 0.84 | HDAC1 (0.34) | GHSRHDAC1HDAC7TACR1OPRM1 | |
| SCHEMBL8990764 | 0.84 | GHSR (0.59) | GHSRTACR1OPRM1OPRD1HRH4 | |
| SCHEMBL8990748 | 0.82 | GHSR (0.50) | GHSRHDAC1HDAC7TACR1OPRM1 | |
| SCHEMBL8990746 | 0.82 | GHSR (0.50) | GHSRHDAC1HDAC7TACR1OPRM1 | |
| SCHEMBL8991051 | 0.81 | GHSR (0.49) | GHSRHDAC1HDAC7TACR1OPRM1 | |
| SCHEMBL8990927 | 0.80 | GHSR (0.58) | GHSRHDAC1HDAC7TACR1OPRM1 | |
| SCHEMBL8991149 | 0.80 | GHSR (0.37) | GHSRTACR1OPRM1OPRD1AGTR1 | |
| SCHEMBL8990828 | 0.80 | GHSR (0.44) | GHSRHDAC1TACR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |