Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 4/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991149 | 0.94 | GHSR (0.37) | GHSRAGTR1OPRM1OPRD1TACR1 | |
| SCHEMBL8991075 | 0.86 | GHSR (0.46) | GHSRAGTR1OPRM1OPRD1TACR1 | |
| SCHEMBL8995722 | 0.85 | AGTR1 (0.32) | GHSRAGTR1 | |
| SCHEMBL9111808 | 0.84 | GHSR (0.40) | HDAC1HDAC7GHSRAGTR1OPRM1 | |
| SCHEMBL8990728 | 0.84 | GHSR (0.42) | GHSRAGTR1OPRM1OPRD1TACR1 | |
| SCHEMBL8991104 | 0.84 | GHSR (0.38) | GHSRAGTR1OPRM1OPRD1TACR1 | |
| SCHEMBL8990895 | 0.82 | GHSR (0.37) | GHSRAGTR1 | |
| SCHEMBL8991039 | 0.82 | AGTR1 (0.41) | HDAC1HDAC7GHSRAGTR1OPRM1 | |
| SCHEMBL8990756 | 0.80 | AGTR1 (0.36) | GHSRAGTR1TACR1 | |
| SCHEMBL8991115 | 0.79 | AGTR1 (0.36) | GHSRAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |