Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 3/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018611 | 0.85 | LMNA (0.61) | LMNAG6PDIDEENPP2MAPT | |
| SCHEMBL22148182 | 0.84 | G6PD (0.49) | LMNAG6PDIDEUSP28FLT1 | |
| SCHEMBL30168110 | 0.84 | G6PD (0.49) | LMNAG6PDIDEUSP28FLT1 | |
| SCHEMBL22148269 | 0.84 | G6PD (0.49) | LMNAG6PDIDEUSP28FLT1 | |
| SCHEMBL1016807 | 0.80 | LMNA (0.59) | LMNAUSP28AVPR2GPR27MAPT | |
| SCHEMBL27462999 | 0.80 | LMNA (0.50) | LMNAFLT1FLT4KDRAVPR2 | |
| SCHEMBL1019014 | 0.79 | KDM4E (0.60) | LMNAG6PDIDEMAPTGAA | |
| SCHEMBL1558072 | 0.79 | IKBKB (0.50) | LMNAG6PDIDEUSP28FLT1 | |
| SCHEMBL1259363 | 0.79 | LMNA (0.49) | LMNAFLT1FLT4KDRAVPR2 | |
| SCHEMBL8114283 | 0.79 | LMNA (0.49) | LMNAAVPR2GPR27ENPP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168720-C | Aryl alkanoylpyridazines | Ĭ��ר���ɷ�����˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1305465-A | Aryl alkanoylpyridazines | MERCK PATENT GMBH (DE) | 2001-07-25 | — | — | CN | disclosed |
| WO-1995007884-A1 | ALKANEDIAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ARRHYTHMIC AND ISCHAEMIC RHYTHM DISORDERS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1995-03-23 | — | — | WO | disclosed |