Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PPM1B | O75688 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22148269 | 0.87 | G6PD (0.49) | LMNAALDH1A1G6PDIDEKDM4E | |
| SCHEMBL30168110 | 0.87 | G6PD (0.49) | LMNAALDH1A1G6PDIDEKDM4E | |
| SCHEMBL22148182 | 0.87 | G6PD (0.49) | LMNAG6PDIDEKDM4EKMT2A | |
| SCHEMBL2512589 | 0.87 | LMNA (0.64) | LMNAALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL712851 | 0.86 | MAPT (0.57) | LMNAALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL9111968 | 0.85 | LMNA (0.49) | LMNAALDH1A1G6PDIDEKDM4E | |
| SCHEMBL344111 | 0.85 | ALDH1A1 (0.58) | LMNAALDH1A1CYP3A4TDP1ALOX15 | |
| SCHEMBL1462829 | 0.85 | CA2 (0.60) | ALDH1A1CYP3A4TDP1ALOX15KDM4E | |
| SCHEMBL8962352 | 0.84 | LMNA (0.70) | LMNAALDH1A1ALOX15KDM4EHPGD | |
| SCHEMBL2514721 | 0.84 | ALDH1A1 (0.47) | LMNAALDH1A1CYP3A4TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121975754-A | Mesotrione nitroreductase, and encoding gene and application thereof | 江苏省农业科学院 | 2026-05-05 | — | — | CN | disclosed |
| CN-119162138-B | Novel mesotrione nitroreductase Bamnr, and encoding gene and application thereof | 南京农业大学 | 2025-11-28 | — | — | CN | disclosed |
| CN-119286811-B | Mesotrione nitroreductase Mstnr, and encoding gene and application thereof | 南京农业大学 | 2025-10-24 | — | — | CN | disclosed |
| CN-119320755-B | Mesotrione nitroreductase Mtnr, coding gene and application thereof | 南京农业大学 | 2025-10-24 | — | — | CN | disclosed |
| CN-119899813-B | Mesotrione nitroreductase Xhnr, coding gene and application thereof | 南京农业大学三亚研究院 | 2025-06-24 | — | — | CN | disclosed |
| CN-119899812-B | Mesotrione nitroreductase gene Xhctnr, protein encoded by mesotrione nitroreductase gene and application of mesotrione nitroreductase gene | 南京农业大学三亚研究院 | 2025-06-13 | — | — | CN | disclosed |
| CN-119899812-A | Mesotrione nitroreductase gene Xhctnr, protein encoded by mesotrione nitroreductase gene and application of mesotrione nitroreductase gene | 南京农业大学三亚研究院 | 2025-04-29 | — | — | CN | disclosed |
| CN-119899813-A | Mesotrione nitroreductase Xhnr, coding gene and application thereof | 南京农业大学三亚研究院 | 2025-04-29 | — | — | CN | disclosed |
| CN-118480520-B | Mesotrione nitroreductase, and encoding gene and application thereof | 江西师范大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119320755-A | Mesotrione nitroreductase Mtnr, coding gene and application thereof | 南京农业大学 | 2025-01-17 | — | — | CN | disclosed |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | US | disclosed |
| WO-2008021463-A2 | AMINO SUBSTITUTED DIARYL[A,D]CYCLOHEPTENE ANALOGS AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS | ACADIA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| CN-101072755-A | Pyridyl inhibitors of Hedgehog signaling | GENENTECH INC (US) | 2007-11-14 | — | — | CN | disclosed |
| US-20070197502-A1 | AMINO SUBSTITUTED DIARYL[a,d]CYCLOHEPTENE ANALOGS AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS | EK FREDRIK | 2007-08-23 | — | — | US | disclosed |
| EP-1789390-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | Genentech, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007048064-A2 | AMINO-PYRIMIDINES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| WO-2006107948-A9 | USE OF N-DESMETHYLCLOZAPINE AND RELATED COMPOUNDS AS DOPAMINE STABILIZING AGENTS | ACADIA PHARM INC (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2006107948-A2 | USE OF N-DESMETHYLCLOZAPINE AND RELATED COMPOUNDS AS DOPAMINE STABILIZING AGENTS | ACADIA PHARMACEUTICALS INC. (US) | 2006-10-12 | — | — | WO | disclosed |
| US-20060063779-A1 | Pyridyl inhibitors of hedgehog signalling | CURIS ROYALTY LLC | 2006-03-23 | — | — | US | disclosed |
| WO-2006028958-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197502-A1 | AMINO SUBSTITUTED DIARYL[a,d]CYCLOHEPTENE ANALOGS AS MUSCARINIC AGONISTS AND METHODS OF TREATMENT OF NEUROPSYCHIATRIC DISORDERS | CHRM4, CHRM5, CHRM1 | LMNA 4253/4885ALDH1A1 1381/4885CYP3A4 450/4885 |
| US-20090018114-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | LMNA 3611/4885ALDH1A1 1504/4885CYP3A4 1621/4885 |
| US-20060063779-A1 | Pyridyl inhibitors of hedgehog signalling | SHH, GLI1, SMO | LMNA 3716/4885ALDH1A1 2407/4885CYP3A4 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.