Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112135 | 1.00 | LTA4H (0.34) | LTA4HCARM1PRMT6PRMT8 | |
| SCHEMBL9112083 | 0.98 | LTA4H (0.33) | LTA4H | |
| SCHEMBL9112090 | 0.98 | LTA4H (0.33) | LTA4H | |
| SCHEMBL23872300 | 0.82 | LTA4H (0.42) | LTA4HCARM1PRMT6PRMT8 | |
| SCHEMBL9109827 | 0.80 | POLB (0.32) | — | |
| SCHEMBL9109819 | 0.80 | POLB (0.32) | — | |
| SCHEMBL7227482 | 0.79 | HRH3 (0.43) | LTA4HCARM1PRMT6PRMT8 | |
| SCHEMBL23872301 | 0.79 | HRH3 (0.43) | LTA4HCARM1PRMT6PRMT8 | |
| SCHEMBL10748748 | 0.79 | HRH3 (0.43) | LTA4HCARM1PRMT6PRMT8 | |
| SCHEMBL3423915 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |