⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23872300 | 0.88 | LTA4H (0.42) | — | |
| SCHEMBL7227482 | 0.85 | HRH3 (0.43) | — | |
| SCHEMBL10748748 | 0.85 | HRH3 (0.43) | — | |
| SCHEMBL23872301 | 0.85 | HRH3 (0.43) | — | |
| SCHEMBL21872268 | 0.79 | KDM4E (0.41) | — | |
| SCHEMBL21872472 | 0.77 | SIGMAR1 (0.36) | — | |
| SCHEMBL9112128 | 0.77 | LTA4H (0.34) | — | |
| SCHEMBL9112135 | 0.77 | LTA4H (0.34) | — | |
| SCHEMBL1466735 | 0.76 | LTA4H (0.36) | — | |
| SCHEMBL11953077 | 0.76 | CARM1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1857453-B1 | FLUOROALKYLPYRROLIDINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-20090012119-A1 | FLUOROALKYLPYRROLIDINE DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1857453-A1 | FLUOROALKYLPYRROLIDINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2007-11-21 | — | — | EP | disclosed |