Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109827 | 1.00 | POLB (0.32) | POLBSMN1; SMN2CXCR4RAD52SIGMAR1 | |
| SCHEMBL9112135 | 0.80 | LTA4H (0.34) | — | |
| SCHEMBL9112128 | 0.80 | LTA4H (0.34) | — | |
| SCHEMBL9112083 | 0.78 | LTA4H (0.33) | SIGMAR1 | |
| SCHEMBL9112090 | 0.78 | LTA4H (0.33) | SIGMAR1 | |
| SCHEMBL20244676 | 0.76 | SIGMAR1 (0.38) | CXCR4SIGMAR1 | |
| SCHEMBL1481329 | 0.76 | POLB (0.35) | POLBSMN1; SMN2CXCR4SIGMAR1 | |
| SCHEMBL1481327 | 0.76 | POLB (0.35) | POLBSMN1; SMN2CXCR4SIGMAR1 | |
| SCHEMBL11669571 | 0.76 | CXCR4 (0.54) | POLBSMN1; SMN2CXCR4SIGMAR1 | |
| SCHEMBL9280593 | 0.74 | POLB (0.34) | POLBSMN1; SMN2CXCR4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |