Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077558 | 0.90 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL10817179 | 0.72 | TP53 (0.38) | CYP2D6CYP2C19 | |
| SCHEMBL5023753 | 0.69 | KDM4E (0.35) | — | |
| Formic Acid SCHEMBL1836111 | 0.68 | ADH1B (0.33) | — | |
| SCHEMBL5018135 | 0.67 | ALDH1A1 (0.31) | — | |
| Isobutane SCHEMBL908934 | 0.67 | CYP2D6 (0.35) | CYP2D6CYP2C19 | |
| Formic Acid SCHEMBL4660060 | 0.67 | — | — | |
| SCHEMBL21499418 | 0.65 | KDM4E (0.32) | — | |
| SCHEMBL8733232 | 0.65 | POLB (0.33) | CYP2D6CYP2C19 | |
| Formic Acid SCHEMBL9619062 | 0.64 | TP53 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659188-A4 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS. | AFFYMAX TECH NV (AN) | 1995-11-22 | — | — | EP | disclosed |
| EP-0659188-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-28 | — | — | EP | disclosed |
| US-5420328-A | Esterification with alcohol and hydrolysis | AFFYMAX TECHNOLOGIES, N.V. (AN) | 1995-05-30 | — | — | US | disclosed |
| US-5359115-A | Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate | AFFYMAX TECHNOLOGIES, N.V. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994006808-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-03-31 | — | — | WO | disclosed |