Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21565031 | 0.81 | — | — | |
| SCHEMBL21347351 | 0.77 | MMP3 (0.33) | KDM4ECA2PTGS1MMP12MMP3 | |
| SCHEMBL7077558 | 0.72 | CYP2D6 (0.36) | — | |
| SCHEMBL5023753 | 0.72 | KDM4E (0.35) | KDM4ECA2PTGS1MMP12 | |
| SCHEMBL5018135 | 0.70 | ALDH1A1 (0.31) | CA2 | |
| SCHEMBL6771400 | 0.69 | — | — | |
| Formic Acid SCHEMBL9112408 | 0.65 | CYP2D6 (0.31) | — | |
| SCHEMBL2878176 | 0.63 | — | — | |
| Ethane SCHEMBL6848109 | 0.62 | — | — | |
| SCHEMBL13808459 | 0.62 | CA12 (0.43) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11723914-B2 | Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-08-15 | — | — | US | disclosed |
| US-11697693-B2 | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-07-11 | — | — | US | disclosed |
| US-11697693-B2 | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-07-11 | — | — | US | disclosed |
| US-11672818-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-13 | — | — | US | disclosed |
| US-11672818-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-06-08 | — | — | US | disclosed |
| US-11421044-B2 | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210347918-A1 | NITRIC OXIDE-RELEASING ALGINATES AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2021-11-11 | — | — | US | disclosed |
| US-20210346424-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-11-11 | — | — | US | disclosed |
| US-11072668-B2 | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-07-27 | — | — | US | disclosed |
| US-11026965-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200216571-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2020-07-09 | — | — | US | disclosed |
| US-20190343869-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190322770-A1 | NITRIC OXIDE-RELEASING ALGINATES AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2019-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | NOS2, NOS3, NOS1 | KDM4E 1750/4885CA2 746/4885PTGS1 20/4885 |
| US-20200216571-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | NOS2, NOS3, NOS1 | KDM4E 1750/4885CA2 746/4885PTGS1 20/4885 |
| US-20190343869-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | NOS1, NOS2, NOS3 | KDM4E 2810/4885CA2 942/4885PTGS1 64/4885 |
| US-20190322770-A1 | NITRIC OXIDE-RELEASING ALGINATES AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | NOS1, NOS2, NOS3 | KDM4E 1736/4885CA2 654/4885PTGS1 13/4885 |
| US-20210347918-A1 | NITRIC OXIDE-RELEASING ALGINATES AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | NOS1, NOS2, NOS3 | KDM4E 1736/4885CA2 654/4885PTGS1 13/4885 |
| US-11672818-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS1, NOS2, NOS3 | KDM4E 2810/4885CA2 942/4885PTGS1 64/4885 |
| US-11026965-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS1, NOS2, NOS3 | KDM4E 2810/4885CA2 942/4885PTGS1 64/4885 |
| US-11072668-B2 | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS1, NOS2, NOS3 | KDM4E 1736/4885CA2 654/4885PTGS1 13/4885 |
| US-11697693-B2 | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS1, NOS2, NOS3 | KDM4E 1736/4885CA2 654/4885PTGS1 13/4885 |
| US-11421044-B2 | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto | NOS2, NOS3, NOS1 | KDM4E 1750/4885CA2 746/4885PTGS1 20/4885 |
| US-11723914-B2 | Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS2, NOS1, NOS3 | KDM4E 448/4885CA2 981/4885PTGS1 54/4885 |
| US-20210346424-A1 | NITRIC OXIDE-RELEASING CYCLODEXTRINS AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | NOS1, NOS2, NOS3 | KDM4E 2810/4885CA2 942/4885PTGS1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.